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Perhaps there is no accurate ranking of the nine masters of the arena.But one emperor is recognized as the strongest.This is the fact that jason is explaining in the gossip he saw in the library in the sihai gang.

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Not to mention the first victory, the big dragon head cui longwang has also united with the knife lord , but he is still at a disadvantage to the leader of the resurrection religion , which makes jason vigilant.

The one who was chasing my father seemed to be my father is junior brother.When he was in front of my father and mother, he rolled over and fell to the ground, twitching all over, screaming while twitching, I am crazy, take me back valley healing.

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After confirming that the food was in hand, jason looked at the remaining food.

But jia youcai did not dare to neglect at all.He knew that from this moment on, the sky in the mountain city had changed.As long as li deshang makes it through.That mountain city is really surnamed li.Is not it settled jason stood on the roof of his room watching the sudden increase of soldiers in the city.

The muffled sound was mixed with a series of sounds of broken bones.The charging attacker slammed his feet off the ground and slammed into the arms of the accomplices behind him.

The bottle in my hand it is a bit of venom that I collected under supervision.

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If you know, that is fine.The onmyoji family does not reject such bloodlines.Even, to some extent, quite welcome.But if you do not know.What is jason is plan no wonder master tongshou temple left jason in tongshou temple this guy has to keep an eye on it keep an eye on it the wandering onmyoji thought in his heart, but .

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Although the contact time is not much, li deshang knows the temper of the warriors.

When the tremor reached an extreme, the scorching heat distorted the air.A low muffled sound echoed in the room.This punch.The air is different from the real thing, and some subtleties cannot be experienced.

Hide it is fine here.Jason grinned and walked to the middle of the deck as he spoke.Then, just closed his eyes.What does it mean exposed, not hidden at all.If someone sees it like this.Wait just for those guys to see at a glance those bastards must have thought we were hiding, but when they got on the deck and suddenly found us standing there, they must have been caught off guard and had no idea what we were doing.

Then, after taking two steps, how do you relieve pain in the bottom of your foot he suddenly remembered something.As a good employer, I hope you do not return to tongshou temple for a while, there are troubles going on there.

The first person surnamed li was already thin enough, but this zhang ming was even thinner.

Could it be that he came back to buy oranges what are you going to do now jason does not like circling conversations, especially when he is in control and the interlocutor is a collaborator.

Where are your parents this is a fortunate thing.My parents traveled outside the island.Otherwise, at their age, I am afraid they would not be able to withstand such torture.

Relying on the habits of many years and the tenacity of his own character, uesugi is breathing heavily.

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The men with sticks followed behind.In front was a team of five people holding torches.Jia youcai was driving, with jason, li deshang and xu dashan sitting in the car.

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Qingshan pirates boss is fine.The second child was staggering.Immediately, the remaining three members of the five monsters of mount dabei waved their mace up together.

There are reasons, there are excuses.Li deshang obviously wants to seize this opportunity.However, this has little to do with jason.He just needs to get his share from li deshang.In this regard, jason has considerable confidence.After all, their initial cooperation was very successful, and li deshang also showed his sincerity the food in zuixianlou was still very anxiety disroder good, especially if he had to eat three meals, especially the drunken immortal chicken.

The next time the other party shows up, you can ask.The uninvited guest finally came to him.There was no sudden attack, and there was no severe means, just a gun pressed against the eyes of jason is mask.

Jia youcai is face was pale, and he gritted his teeth and did not spit it out.

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Such a shout instantly attracted the attention of the snitch.The different head catching costumes immediately attracted the attention of the other li4 acupressure point location party.

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It is a worthless business.However, he has a good reputation, and he will not do anything that kills people, mostly for money.

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Everyone was stunned.Is it because we are here that you can not cast more powerful secret techniques tsuchimikado asked softly.

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He still wants to live.He is a profitable businessman.Just make money.Reducing the smile on his face, the intelligence monger began to speak sternly.

Yes, xiao zhao.The female assassin who was firmly bound to the ground smiled.It is the kind of smile that is three point cool, three point disdain, and four point nonchalant.

And this is more difficult.The right time and place are indispensable.It is far better to enter the big forces and browse the collections of the big forces.

The musket team of more than ten people was divided into two rows, one in front and one behind.

He did not want to take another look at jia youcai, so he put it on jason.Jia youcai did not care.The head catcher picked up the tea on the table, drank it, took two breaths, and continued talking.

Demon I do not know who said those words.This is also the voice of everyone at this moment.It is timidity.These thugs were originally hyenas and vultures on the battlefield.They come for money.Although the mouth says promise, .

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While sewing, the bean bag said, have you seen the thread end, the pavilion master when you were fighting, you pinched the thread end with your hand, and then punched hard, and the lime in the sleeve was scattered remember, the left sleeve is ordinary lime, the right sleeve I mixed with croton powder, the left trouser leg I mixed with aconitum powder, and the right trouser leg I mixed with lily of the valley powder.

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Overactive bladder syndrome or OAB is a condition where one feels an uncontrollable and sudden urge to urinate.

OAB or urinary incontinence is caused when the bladder muscles or detrusor muscles involuntarily contract. These contractions can cause a person to urinate regardless of urine volume in the bladder.

Some conditions that may cause a person to experience OAB include diabetes, urinary tract infections, bladder stones or tumors, stroke, Parkinson’s d isease, multiple sclerosis (MS) , or hormonal changes.

A person with OAB may pass urine several times a day. Persons with this condition may experience emotional stress, interrupted sleep cycles, or sexuality issues affecting their social or work life (4) .

Existing Medications

Some behavioral changes may allow a person to manage OAB and improve bladder control and overall wellness.

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For OAB , other treatment options include taking prescription drugs, Botox injections, nerve stimulation, and surgery (6) .

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A pilot study by Maniscalco , Aponte , Bruzzese , and other researchers on the effects of cannabidiol on patients with multiple sclerosis OAB was conducted in 2017.

The researchers conducted clinical trials on several MS patients and evaluated leakage , detrusor muscle pressure, and spasticity .

The observation was done before and after tetrahydrocannabinol – cannabidiol oromucosal spray was applied to the patients.

Urodynamic findings after the treatment indicated a significant reduction of post-void residual volume. Bladder volume at the first desire and maximal cystometric capacity also increased. However, the amounts were insignificant.

The results showed that THC – CBD oromucosal sprays may improve bladder symptoms and detrusor overactivity (8) .

A 2010 review was published in the Indian Journal of Urology on the role of cannabinoid receptors in the bladder . T he researchers said that endocannabinoid receptors CB 1 and CB 2 in the bladder periphery may contribute to controlling bladder stimulus (9) .

Cannabinoids extracted from the Cannabis plant , like CBD , CBG , and THC , affect the CB 1 and CB 2 receptors . Unlike THC , CBD has no psychoactive effect characterized by a high sensation.

As of 2021, CBD has only been approved by the FDA to treat epilepsy (10) . Studies are still ongoing to determine and confirm the efficacy of CBD and medical marijuana on OAB .

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CBD may help manage various illnesses like neuroinflammation, epilepsy, vomiting and nausea, oxidative injury, and anxiety (11) .

Neuroinflammation is an inflammatory response in the central nervous system associated with various diseases like multiple sclerosis and stroke (12) . These diseases are some of the conditions that can trigger bladder dysfunctions like OAB .

CBD works by interac ting with the endocannabinoid system. The ECS contains receptors that regulate various body functions (13) , like CB 1 receptors in the central nervous system responsible for regulating inflammatory responses.

Can CBD Be Used to Manage Overactive Bladder Conditions?

The study by Maniscalco and colleagues showed that CBD as an oromucosal spray may effectively manage OAB (14) .

More clinical trials must be conducted to determine if other CBD oil products are as effective as THC – CBD oromucosal sprays .

How CBD Works on the Bladder

CBD may affect the bladder through the ECS, particularly the CB 1 and CB 2 receptors . This effect may help with controlling bladder stimulus (15) .

CBD also affects the ECS receptors that regulate inflammatory responses triggered by various neurological conditions like MC or stroke. These neurological conditions are known to cause OAB (16) .

Does CBD Create a Positive Effect on the Bladder?

The results from the 2017 study by Maniscalco and his team showed that CBD may have a favorable impact on detrusor muscle activity and help manage OAB symptoms (17) .

CBD is well tolerated and does not have the same psychoactive effects as THC , although both compounds are Cannabis extracts. However, the use of CBD may still cause side effects like diarrhea, reduced appetite, dry mouth , and fatigue (18) .

Patients with OAB are encouraged to consult a physician or professional health worker to determine if CBD is a practical option in managing OAB .

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